The current state of the problem of tick-borne encephalitis in Russia and the world

Relevance . Despite the successes achieved over 85-year history of study tick-borne encephalitis (TBE), there are still many controversial and unresolved issues. It is obvious that in second decade XXI century, this natural focal neuroinfection, as before, poses a great threat to public health not only Russia, but also endemic countries world. Aim To present modern aspects etiology, epidemiology, diagnosis, specific prevention TBE Russia Conclusions Currently, 4 genotypes virus: Far Eastern, European, Siberian Baikal, each which has its own area, pathogenic potential for humans. Nosoareal covers most territory 29 European countries. Cases disease or viral activity registered six Asian For correct verification criteria diagnosis cases have been developed, mainly concern unvaccinated persons. Since highly effective etiotropic drugs treatment yet strategy reducing incidence mass vaccination population regions. Due increase rate countries, order improve epidemiological surveillance TBE, standards laboratory among vaccinated persons, clarification causes vaccinated, well deaths them, need be clarified. In conditions combination foci other infections, it important develop diagnostic algorithms, including differential with infections transmitted by Ixodic ticks.